If it seems when you click Quotes/Orders from the main menu that the screen is really slow to open, or doesn't open at all, the most likely cause is that an inappropriate sort column has been selected.
Only some fields are good for sorting from that screen, and if you have more than 10000 orders in your list, then even though you have the ability to sort by a column, it doesn't always make sense and sometimes it will drastically slow down that screen.
To reset the sorting, you simply need to wait on the screen to refresh (it could take a LONG time if you have a lot of orders in your list - but just keep waiting; eventually it will refresh). Once the screen is redrawn, click the Reset button at the upper right corner under the Search button, and then close the screen with the X at the upper right. That will usually resolve the problem.
Also, if you have a large database, make sure that on the Clients/Contacts and Quotes/Orders list screens that you turn off the "Show Grid Before Search" option (open the screen, right-click on the grid, uncheck the "Show Grid Before Search" option). If you leave this check, then whenever that screen is opened, it runs a query that retrieves every record in your database, when really, you don't want it to do that if you have a large database. You just want it to give you the search box, and so then it will only retrieve the matching records.
In addition, you can speed up search by limiting the fields that are searched in on this screen. Refer to this topic for help with that:
How do I select different search fields on the Quote / Order List screen?
order list slow invoice list slow find order find quote slow find quote/order slow quotes/orders list won't open
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